The Orthodox View of Brain Sexual Differentiation

摘要: The standard view of sexual differentiation the brain, derived primarily from work with mammals, is that same steroidal signal which permanently masculinizes body early in life, androgen, also nervous system. This oversimplified overlooks rich diversity mechanisms produced by natural selection. We review underlying what may be simplest mammalian model, spinal nucleus bulbocavernosus (SNB), a system intimately associated periphery. Indeed, many instances, androgen can masculinize SNB but, surprisingly, these influences depend to some extent on social mediating factors. Furthermore, adulthood, continues affect diverse ways, acting several different loci, indicating life-long plasticity even this simple Finally, there evidence adult androgens interact experience order Thus displays far richer array interactions than would predict. Examination other systems and species, as depicted following reports, reveals more complicated, interesting perspective how brains behaviors males females diverge.