Risk factors of venous thromboembolism in focal segmental glomerulosclerosis with nephrotic syndrome
作者： Shi-jun Li , Yuan-Mao Tu , Chang-sheng Zhou , Li-Hua Zhang , Zhi-hong Liu
DOI: 10.1007/S10157-015-1149-4
关键词: Focal segmental glomerulosclerosis 、 Medicine 、 First episode 、 Pulmonary embolism 、 Venous thrombosis 、 Hypoalbuminemia 、 Internal medicine 、 Nephrotic syndrome 、 Portal vein thrombosis 、 Renal vein thrombosis
摘要: Venous thromboembolism (VTE) is an important and potentially life-threatening complication in focal segmental glomerulosclerosis (FSGS). The aim of this study was to investigate the prevalence predisposing risk factors venous patients with FSGS nephrotic syndrome. A total 120 syndrome were enrolled study. confirmed by contrast-enhanced dual-source computed tomography angiography or magnetic resonance venography. Potential clinical laboratory for VTE screened. thrombosis demonstrated 12 (10 %) patients. occurred during first episode 3 a relapse 9 Eight had pulmonary embolism, four renal vein thrombosis, three lower limb deep one cerebral sinovenous portal thrombosis. positive predictive value D-dimer level 22.4 % FSGS, negative 100 %. Of screened factors, higher hematocrit VTE. Other such as proteinuria, hypoalbuminemia, platelet count, fibrinogen level, antithrombin III not FSGS. We found that approximately 10 % Most PE. Hemoconcentration development Negative may exclude
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