Identification of 17α,20β,21-trihydroxy-4-pregnen-3-one as the major ovarian steroid produced by the teleost Micropogonias undulatus during final oocyte maturation

作者: John M Trant , Peter Thomas , Cedric H.L Shackleton

DOI: 10.1016/0039-128X(86)90081-4

关键词: Alpha (ethology)EndocrinologyMicropogoniasOocyteAndrologyOvarySteroidBiologyInternal medicineBeta (finance)MetabolismEnzyme

摘要: This study describes the identification of 17 alpha,20 beta, 21-trihydroxy-4-pregnen-3-one (20 beta-dihydro-11-deoxycortisol, 20 beta-S) as a major steroid product ovary Atlantic croaker (Micropogonias undulatus) incubated in vitro. is first report which beta,21-trihydroxy-4-pregnen-3-one teleost steroidogenic tissue. The was identified by variety methods, including HPLC, TLC, GC-MS, UV absorbance, and reactions with specific enzymes. Full grown oocytes, prior to final oocyte maturation (FOM), accumulated only small amounts beta-S. However, substantial increase beta-S production occurred at time FOM. These results suggest that maturational this species.

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