Frequency of Abnormal Carbohydrate Metabolism and Diabetes in a Population-based Screening of Adolescents

摘要: Objective To document the frequency of glucose intolerance in adolescents a population-based study primarily African-American/Non-Hispanic whites an urban-suburban school district. Study design Measurement fasting and 2-hour post-glucose load plasma concentrations. Results Carbohydrate (either impaired glucose, tolerance, or both) was identified 8.0%, near-diabetes (1 ≥126 mg/dL [7.0 mmol/L] and/or ≥200 [11.1 mmol/L]) 0.3%, diabetes 0.36% (type 1A = 0.24%; type 2 = 0.08%; undiagnosed 2 = 0.04%). A model for abnormal carbohydrate metabolism constructed with regression analysis Intoelrance (CI)/near-diabetes group logistic entire population. Risk factors development CI/near-diabetes included having 1 unit increase body mass index (BMI) z-score either being non-Hispanic white pubertal group. Increased correlated puberty decreased BMI z-score, whereas increased z-score. By using National Health Nutrition Survey (NHANES) III (1988-1994) definitions, present 2.0% this versus 1.7% (NHANES III). Conclusion The prevalence 8.3%. Undiagnosed mellitus rare. One third could be classified as 2 mellitus. adult progression insulin resistance to may valid. Despite overweight population since NHANES III, abnormalities have not changed significantly.