Some metabolic relationships between biopterin and folate: implications for the "methyl trap hypothesis".
作者： Seymour Kaufman
DOI: 10.1007/BF00965847
关键词: Tetrahydrobiopterin 、 Metabolic pathway 、 Methylenetetrahydrofolate reductase 、 Cyanocobalamin 、 Biochemistry 、 Biosynthesis 、 Biopterin 、 Chemistry 、 Cofactor 、 Metabolism
摘要: Tetrahydrobiopterin and the folate coenzymes can reciprocally interact in ways that would be useful to metabolic pathways subserved by both of these coenzymes. Thus, through one reactions catalyzed methylene tetrahydrofolate reductase, 5-CH3-H4-folate regenerate BH4 from q-BH2 provide an escape "methyl trap."
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