Monitoring Peri-Therapeutic Cerebral Circulation Time: A Feasibility Study Using Color-Coded Quantitative DSA in Patients with Steno-Occlusive Arterial Disease

摘要: BACKGROUND AND PURPOSE: Intracranial hemodynamics are important for management of SOAD. This study aimed to monitor peri-stent placement intracranial CirT patients with SOAD. MATERIALS METHODS: Twenty-five received stent extracranial ICA stenosis, and 34 normal were recruited as controls. Their color-coded DSAs used define the Tmax selected intravascular ROI. A total 20 ROIs ICA, OphA, ACA, MCA, FV, PV, OV, SSS, SS, IJV, MCV selected. rTmax was defined at region interest minus cervical segment (I1 on AP view IA lateral view). PV CirT. Intergroup intragroup longitudinal comparisons performed. RESULTS: values cohorts follows: ICA-AP, 0.12; ICA-LAT, 0.10; A1, 0.28; A2, 0.53; A3, 0.81; M1, 0.40; M2, 0.80; M3, 0.95; 0.35; 4.83; 5.11; 5.17; 6.16; 6.51; 6.81; MCV, 3.86 seconds. Before placement, arterial ROIs, except A3 prolonged compared from control subjects ( P < .05). None any venous in stenotic group significance. After all shortened significantly, A1and M3. Poststenting not different group. CONCLUSIONS: Without extra contrast medium radiation dosages, quantitative DSA enables real-time monitoring peri-therapeutic SOAD . AP : anterior-posterior view AUC : area under ROC curve CI : confidence interval CirT : circulation time FV : cortical veins frontal region ICA-AP : internal carotid artery view ICA-LAT : view ICC : intraclass correlation coefficient IJV : jugular vein MCV : middle cerebral vein OphA : ophthalmic artery OV : occipital region PV : parietal region rTmax : relative Tmax ROC : receiver operating characteristic SOAD : steno-occlusive disease SS : sigmoid sinus SSS : superior sagittal sinus Tmax : time maximum opacification