Sarcoidosis: Role of non-tuberculosis mycobacteria and Mycobacterium tuberculosis

摘要: Sarcoidosis is a granulomatous inflammatory disease that induced by unknown antigen(s) in genetically susceptible host. Although the direct link between Mycobacterium tuberculosis (MTB) infection and sarcoidosis can be excluded on basis of current knowledge, non-infectious mechanisms may explain causative role mycobacterial antigens. Ever since was first described, its relationship with (TB) has been under-investigated. Whereas some researchers consider TB as two examples same process, others have rejected mycobacteria playing any sarcoidosis. Whether they are linked causally or not, clinical evidence makes differential diagnosis conditions very challenging, particularly countries high burden TB. The present study analyzes implications practice. coincidence higher incidence DNA biological samples sarcoid patients reported many authors. In addition, new similarity MTB phenotype provided. Overall, these observations suggest not only share etiology, but even different aspects one disease.