A pyroelectric-based system for sensing low abundant lactose molecules
作者： Romina Rega , Juan Francisco Muñoz Martinez , Martina Mugnano , E. Oleandro , Oriella Gennari
DOI: 10.1117/12.2531770
关键词: Materials science 、 Chromatography 、 Pyroelectricity 、 Lab-on-a-chip 、 Biosensor 、 Scanner 、 Diffusion 、 Lactose 、 Microscale chemistry 、 Fluorescence
摘要: A novel method for sensing low abundant lactose in small sample volumes is proposed. It based on a pyroelectrodynamic jet (p-jet) system able to concentrate the molecules onto solid amine support easy and rapid detection through fluorescence measurement. The p-jet produces droplets with sub-picoliter accumulated microscale area of order reduce diffusion limits typically occurring standard well-based assays. highly reproducible linear response was obtained between 2 pM/μL 10 pM/μL. great advantage technique ability directly ready readout measurement by scanner. No time-consuming expensive treatments are needed. proposed rapid, suitable repeated use providing built-in quality assurance.
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