Could Naturally Occurring Coronaviral Diseases in Animals Serve as Models for COVID-19? A Review Focusing on the Bovine Model.
作者： Jonas Johansson Wensman , Maria Stokstad
关键词: Population 、 Pandemic 、 Coronavirus 、 Biology 、 Respiratory infection 、 Virus classification 、 Virology 、 One Health 、 Disease 、 Betacoronavirus 1
摘要: The current pandemic of COVID-19 has highlighted the importance basic studies on coronaviruses (CoVs) in general, and severe acute respiratory syndrome CoV type 2 (SARS-CoV-2) particular. CoVs have for long been studied veterinary medicine, due to their impact animal health welfare, production, economy. Several models using coronaviral disease natural host suggested. In this review, different are discussed, with main focus bovine (BCoV). BCoV is endemic cattle population worldwide known several decades. SARS-CoV-2 both betacoronaviruses, where highly similar human coronavirus (HCoV) OC43, encompassing same virus species (Betacoronavirus 1). causes gastrointestinal young adult cattle. This review summarizes knowledge similarities dissimilarities between SARS-CoV-2, as well discussing usage a model CoVs, including SARS-CoV-2.
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