A JARID family demethylase controls differentiation timing through global effects on transcription.

作者: Kitty F. Verzijlbergen , Adele L. Marston

DOI: 10.1016/J.MOLCEL.2012.11.014

关键词: YeastDemethylaseCell typeTranscription (biology)GeneticsBiologyDevelopmental cell

摘要: In a recent issue of Developmental Cell, Xu et al. (2012) show that JARID family H3K4 demethylase delays transcriptional quiescence in yeast to produce robust gametes. Similar mechanisms may alter programs other differentiating cell types.

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