Selected Physiological Effects of a Garcinia Gummi-Gutta Extract in Rats Fed with Different Hypercaloric Diets

摘要: Garcinia gummi-gutta (GGG) rind extract is effective for reducing appetite, body weight and adiposity of obese rodents fed high-fat (HF), high-sugar (HS) or high fat/sugar (HFS)-based diets, but these effects have not been simultaneously evaluated. Thirty (~425 g) male Wistar rats were eleven weeks with six hypercaloric diets (4.1 kcal/g; five rats/diet) non-supplemented (HF, HS, HFS), supplemented (HF+, HS+, HFS+) GGG (5.9%), while from the control group (375 a normocaloric diet (3.5 kcal/g). Body weight, dietary intake, fat distribution, histological biochemical parameters recorded. Compared to rats, groups consumed significantly less food (14.3% 24.6% (−4.3 g/day), respectively) (p > HF+, no signs toxicity in testes observed. The results indicate that more when co-administered HF rats.