Congenital hypothyroidism, as studied in rats. Crucial role of maternal thyroxine but not of 3,5,3'-triiodothyronine in the protection of the fetal brain.
作者： R Calvo , M J Obregón , C Ruiz de Oña , F Escobar del Rey , G Morreale de Escobar
DOI: 10.1172/JCI114790
关键词: Endocrinology 、 Euthyroid 、 Thyroid function 、 Congenital hypothyroidism 、 Transplacental 、 In utero 、 Triiodothyronine 、 Fetus 、 Internal medicine 、 Pregnancy 、 Medicine
摘要: … 3,5,3'-triiodothyronine (T3) in congenital hypothyroidism,we gave pregnant rats methimazole (MMI), … MMI treatment resulted in marked fetal T4 and T3 deficiency. Infusion of T4 into the …
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