Synthesis, Characterization and Bioactivity Studies of Novel β-chitin Scaffolds for Tissue-engineering Applications
作者： Y. Maeda , R. Jayakumar , H. Nagahama , T. Furuike , H. Tamura
DOI: 10.1016/J.IJBIOMAC.2008.03.002
关键词: Chemical engineering 、 Polymer chemistry 、 Simulated body fluid 、 Thermogravimetric analysis 、 Chemistry 、 Biodegradation 、 Aqueous solution 、 Calcium 、 Chitin 、 Tissue engineering 、 Biopolymer
摘要: Abstract Chitin is a biopolymer and it non-toxic, biodegradable biocompatible. has many potential industrial applications because of its abundance, biodegradability, non-toxicity, chemical inertness. β-Chitin scaffolds were prepared by using saturated calcium chloride alcoholic solution (CaCl 2 ·6H O/EtOH) then followed dialysis with lyophilization. The β-chitin characterized FT-IR, scanning electron microscopy (SEM) thermogravimetric (TGA). preliminary bioactivity studies studied simulated body fluid (SBF) for 7, 14 21 days. We also immersed the in aqueous CaCl Na HPO 4 over 12 h. After days, SEM FT-IR studies. showed that there phosphate layer surface as well cross-section scaffolds. It seems are useful tissue-engineering field.
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