Development of the Taste System

摘要: The taste system of vertebrates is composed an array peripheral, multicelluar receptor organs, termed buds, which are innervated by branches specific cranial nerves, in turn convey information from the periphery to central nervous system. Each these elements develops separate and discrete embryonic tissues, yet must connect during embryogenesis order that a fully functional present as newborn begins feed. In past decade, researchers have made significant advances our understanding molecular, cellular, tissue-level mechanisms driving development several components this It now well established oral epithelium destined produce buds patterned quite early embryogenesis, independently ingrowing nerve fibers. Moreover, genes required for normal bud patterning been identified. innervation has also received substantial attention, such factors known regulate proper connectivity between developing Importantly, implementation molecular genetic approaches mice contributed significantly progress, comparison with findings other model developmental systems, including amphibians.