4.8 Myosin Motors: Structural Aspects and Functionality
作者： M. Preller , D.J. Manstein
DOI: 10.1016/B978-0-12-374920-8.00410-0
关键词: Actin 、 Transient kinetics 、 Myosin 、 Biophysics 、 Allosteric regulation 、 Motor protein 、 Biology 、 Cellular functions 、 Molecular dynamics
摘要: In this chapter, the authors present an overview of myosin family actin-based motors. Properties members individual subfamilies are described and diversity myosin-domain structures cellular functions is outlined. The motor as intrinsic allosterically regulated protein providing ample opportunities to apply biophysical approaches study mechanism chemomechanical coupling allosteric communication in proteins. field has been consistently vanguard applying emerging techniques structural functional characterization chapter includes examples from X-ray crystallography, electron microscopy, transient kinetics, single-molecule spectroscopy, molecular dynamics, hybrid employing combinations two or more these methods.
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