ACUTE AND CHRONIC STRESS EXPOSURE PREDICTS 1‐YEAR RECURRENCE IN ADULT OUTPATIENTS WITH RESIDUAL DEPRESSION SYMPTOMS FOLLOWING RESPONSE TO TREATMENT

摘要: BACKGROUND: One of the strongest predictors depression recurrence in those who respond to treatment is presence residual depressive symptoms. Our goal was examine stressful life event exposure as a mechanism previously depressed patients with That is, we predicted that higher levels symptoms will significantly predict acute events then heighten prospective risk. METHODS: Participants included 68 adult outpatients major (42 women; age 18-60) completed 12-month naturalistic follow-up after achieving remission 20-week randomized, open label trial interpersonal psychotherapy, cognitive-behavioral therapy, or antidepressant medication. Depression defined reemergence an episode determined by structured interview. Acute and chronic stressors were assessed at end using contextual RESULTS: Posttreatment scores prospectively increased risk for recurrence, period. Cox regression survival analyses modeling time-dependent covariates showed mediated relation even controlling stress. CONCLUSIONS: findings implicate heightening through events. adds burden disorder. Therefore, rigorous targeting context has potential prevent lifelong pattern illness. Language: en