Spectroscopic Tools in the Study of Micelles and Membranes

摘要: After an overview of possibilities to determine the location probe molecules in microheterogeneous media (1H-NMR and absorption spectra), measurements with probes micelles synthetic biological membranes are discussed. These report on fluidity, polarity polarizability their environment. The can be investigated using spectra (E-p(30)), fluorescence (Ham effect, pyrene), lifetimes (pyrene derivatives), intramolecular hetero-excimer mixed excimer formation. fluidity is studied employing dipyrenylpropane (Py(3)Py), for which kinetics formation Further, a number precautions that have taken into account when Py(3)Py treated. Also, occurrence self aggregation amphiphilic presented. Information derived from spectra. It concluded aqueous micellar solutions ionic surfactants water present around at least three carbon atoms down polar head group. Ionic modelled as spherical structures groups predominantly surface terminal methyl mainly central region. environment surprisingly high. This attributed presence having non-bulk properties Fluidity studies reveal (phosphatidylcholines) or absence (human erythrocyte ghosts) thermotropic phase transitions, well changes, function temperature, structure sarcoplasmic reticulum membranes.