Towards biocompatible nano/microscale machines: self-propelled catalytic nanomotors not exhibiting acute toxicity

摘要: Recent advances in nanotechnology have led to the evolution of self-propelled, artificial nano/microjet motors. These intelligent devices are considered be next generation self-powered drug delivery system field biomedical applications. While many studies strived further improve various properties these such as their efficiency, performance and power, little attention has been paid actual biocompatibility nanojets vivo. In this paper, we will present for first time investigation toxicity effects on viability human lung epithelial cells (A549 cells). From 24 h 48 post-exposure studies, it is clearly shown that used our work negligible influence cell across all concentrations tested. As such, profile neither dose- nor time-dependent. This strongly indicative benign nature nanojets, which paramount significance step towards applications nano/micromotors real-world practical medical devices.