Advances in Our Understanding of Immunosuppression as a Risk Factor for Cutaneous SCC: Evidence for Revision of Immunosuppressive Therapy

作者: Günther F. L. Hofbauer , Chantal C. Bachmann

DOI: 10.1007/978-3-319-12445-2_4

关键词: Organ transplantationInternal medicineMerkel cell carcinomaSkin cancerBasal cell carcinomaMedicineMelanomaDermatologyRisk factorSarcomaOncologyImmunosuppression

摘要: Organ transplant recipients (OTRs) on immunosuppressive therapy are at increased risk of nonmelanoma skin cancer (NMSC) including epithelial cancer, Merkel cell carcinoma, and Kaposi’s sarcoma, as well other transplant-associated cancers compared to the normal population [1]. Squamous carcinoma (SCC) is a major complication treatment with drugs, 65- 100-fold higher than in [2]. Other malignancies like basal (BCC), melanoma, internal increase but significantly lesser extent [3].

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