Stretch-stimulated glucose uptake in skeletal muscle is mediated by reactive oxygen species and p38 MAP-kinase.

作者: Melissa A. Chambers , Jennifer S. Moylan , Jeffrey D. Smith , Laurie J. Goodyear , Michael B. Reid

DOI: 10.1113/JPHYSIOL.2008.165639

关键词: Internal medicineReactive oxygen speciesEndocrinologyGlucose transporterSkeletal musclePhosphatidylinositolWortmanninBiologyProtein phosphorylationAMP-activated protein kinaseGlucose uptake

摘要: … 2C) and stretched myotubes (Fig. 2D). We demonstrate for the first time stretch increased oxidant activity in both EDL and myotubes. To determine the nature of the oxidant activity, we …

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