Fools rush in

作者: Helen Piwnica-Worms

DOI: 10.1038/44029

关键词: CellCell biologyCHEK1Dividing cellCell cycleBiologyCyclin AProtein p53DNA

摘要: When a dividing cell's DNA is damaged, that cell needs to stop so the damage can be repaired. There are two main points at which cell-division cycle halted. A study of one these -- G2 DNA-damage checkpoint shows there parts control. The first, initiation, does not seem depend on tumour-suppressor protein p53. But maintenance this checkpoint, it seems, does.

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