作者: Trevor Castor
DOI:
关键词: Polymeric microspheres 、 Biodegradable polymer 、 Polymer 、 Supercritical fluid 、 Solubilization 、 Nanotechnology 、 Microsphere 、 Materials science
摘要: This invention is for an improved process to formulate polymeric microspheres/nanospheres and encapsulate therapeutic proteins other useful substances. Non-toxic supercritical or near-critical fluids with/without polar cosolvents are utilized solubilize biodegradable polymers form uniform polymer microspheres nanospheres with controlled-release characteristics.