Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products

作者: Trevor Castor

DOI:

关键词: Polymeric microspheresBiodegradable polymerPolymerSupercritical fluidSolubilizationNanotechnologyMicrosphereMaterials science

摘要: This invention is for an improved process to formulate polymeric microspheres/nanospheres and encapsulate therapeutic proteins other useful substances. Non-toxic supercritical or near-critical fluids with/without polar cosolvents are utilized solubilize biodegradable polymers form uniform polymer microspheres nanospheres with controlled-release characteristics.