作者: L M Brosseau
DOI: 10.1191/0960327102HT266XX
关键词: Occupational exposure limit 、 Environmental health 、 Medicine 、 Hormesis 、 Adverse effect 、 Health outcomes 、 No-observed-adverse-effect level 、 Occupational hygiene
摘要: Hormesis is an appealing concept when considered from the evolutionary viewpoint. It may provide a new approach to deriving `no observed adverse effect level’ for occupational exposures chemicals. An over-reliance on mathematical modeling without clear understanding of and health outcomes stymies current scientific decision-making. Care must be taken, however, as not all endpoints will exhibit hormetic response.