Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
作者： Alan M. Fogelman , Mohamend Navab
DOI:
关键词: Oral route 、 Biochemistry 、 Amino acid 、 Peptide 、 Amphipathic helix 、 Stereochemistry 、 Organic molecules 、 Inflammatory response 、 Apolipoprotein B 、 Chemistry
摘要: This invention provides novel active agents (e.g. peptides, small organic molecules, amino acid pairs, etc.) peptides that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the resemble a G* amphipathic helix apolipoprotein J. The are highly stable and readily administered via oral route.
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