Active Serum Vitamin D Levels Are Inversely Correlated With Coronary Calcification

摘要: Background Arterial calcification is a common feature of atherosclerosis, occurring in >90% angiographically significant lesions. Recent evidence from this and other studies suggests that development atherosclerotic similar to osteogenesis; thus, we undertook the current investigation on potential role osteoregulatory factors arterial calcification. Methods Results We studied two human populations (173 subjects) at high moderate risk for coronary heart disease assessed them associations between vascular serum levels molecules osteocalcin, parathyroid hormone, 1α,25-dihydroxyvitamin D3 (1,25-vitamin D). Our results revealed 1,25-vitamin D are inversely correlated with extent both groups. No correlations were found osteocalcin or hormone. Conclusions These data suggest possible vitamin calcification. Vitamin also known be important bone mineralization; may one factor explain long observed association osteoporosis