Mitochondrial dysfunction leads to telomere attrition and genomic instability
作者： Lin Liu , James R. Trimarchi , Peter J. S. Smith , David L. Keefe
DOI: 10.1046/J.1474-9728.2002.00004.X
关键词: Telomere 、 Reactive oxygen species 、 Genome instability 、 Oxidative stress 、 Biology 、 Apoptosis 、 Mitochondrion 、 Cell biology 、 Genome 、 Senescence
摘要: Mitochondrial dysfunction and oxidative stress have been implicated in cellular senescence, apoptosis, aging and aging‐associated pathologies. Telomere shortening and genomic …
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