SPECIAL ISSUE: DETECTING SELECTION IN NATURAL POPULATIONS: MAKING SENSE OF GENOME SCANS AND TOWARDS ALTERNATIVE SOLUTIONS The rate of adaptive evolution in animal mitochondria

作者： Gwenael Piganeau , Adam Eyre-Walker , Jennifer E. James

DOI:

关键词: Evolutionary biology 、 Mitochondrion 、 Taxonomic rank 、 Animal species 、 Selection (genetic algorithm) 、 Biology 、 Adaptive evolution 、 Nonsynonymous substitution 、 Mitochondrial DNA 、 Genetics 、 Genome

摘要: We have investigated whether there is adaptive evolution in mitochondrial DNA, using an extensive data set containing over 500 animal species from a wide range of taxonomic groups. apply variety McDonald–Kreitman style methods to the data. find that DNA dominated by slightly deleterious mutations, finding which supported number previous studies. However, when we control for presence mutations new method, mitochondria undergo significant amount evolution, with estimated 26% (95% confidence intervals: 5.7–45%) nonsynonymous substitutions fixed evolution. further some weak evidence rate correlated synonymous diversity. interpret this as at least limited supply mutations.

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SPECIAL ISSUE: DETECTING SELECTION IN NATURAL POPULATIONS: MAKING SENSE OF GENOME SCANS AND TOWARDS ALTERNATIVE SOLUTIONS The rate of adaptive evolution in animal mitochondria

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SPECIAL ISSUE: DETECTING SELECTION IN NATURAL POPULATIONS: MAKING SENSE OF GENOME SCANS AND TOWARDS ALTERNATIVE SOLUTIONS The rate of adaptive evolution in animal mitochondria

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