Surfactant Systems: Their chemistry, pharmacy and biology

作者: A. T. Florence , David T. Attwood

DOI:

关键词: PolymerizationPulmonary surfactantMembrane permeabilityEmulsionMicroemulsionAqueous solutionAmphiphileOrganic chemistryMicelleChemistry

摘要: 1. Surface activity.- 1.1 Amphipathic molecules.- 1.2 activity in aqueous solution.- 1.3 Adsorption at liquid surfaces.- 1.4 solid 1.5 The wettability of 1.6 Modification the surface properties solids by adsorbed surfactants.- References.- 2. Phase behaviour 2.1 Introduction.- 2.2 Liquid crystalline phases binary surfactant systems.- 2.3 ternary 2.4 Factors affecting phase behaviour.- 2.5 Quaternary 3. Micellization.- 3.1 3.2 Micellar structure.- 3.3 shape.- 3.4 Polydispersity micellar size.- 3.5 CMC and 3.6 Thermodynamics micelle formation.- 3.7 Kinetics 3.8 Non-micellar association.- 3.9 Micelle formation non-aqueous solvents.- 4. colloidal drugs naturally occurring substances.- 4.1 Colloidal drugs.- 4.2 Some biological consequences drug 4.3 Biological relevance 4.4 Naturally formers: bile salts, phospholipids related 5. Solubilization.- 5.1 5.2 Experimental methods studying solubilization.- 5.3 Mobility solubilizate 5.4 influencing 5.5 Effect on properties.- 5.6 Solubilization 6. Pharmaceutical aspects 6.1 6.2 6.3 solubilization 6.4 with block co-polymeric 6.5 Polymer-surfactant interactions.- 6.6 Surfactant interactions oppositely charged species.- 6.7 Hydrotropy pharmaceutical 7. implications presence formulation.- 7.1 7.2 surfactants dissolution 7.3 membrane permeability.- 7.4 absorption.- 7.5 Miscellaneous formulations influence 7.6 Surfactants antibacterial 7.7 Utilization delivery 8. Emulsions.- 8.1 8.2 Aspects emulsion stability.- 8.3 Multiple emulsions.- 8.4 Microemulsions.- 8.5 Viscosity rheological characteristics 8.6 Solute disposition 8.7 Biopharmaceutical 9. suspension 9.1 9.2 Settling suspended particles.- 9.3 Suspension 9.4 adsorptive capacity suspensions.- 9.5 Rheological 9.6 Crystal changes 9.7 Bacterial other cell 10. toxicity.- 10.1 10.2 Metabolism 10.3 Interactions membranes components.- 10.4 Toxicology 10.5 plant 11. Reactivity 11.1 11.2 Chemistry interfaces.- 11.3 reactions.- 11.4 Stability 11.5 11.6 Polymerization surface-active 11.7 analytical presence.- References.

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