A short review of primary aldosteronism in a question and answer fashion

摘要: Objectives The aim of this study was to present up date information concerning the diagnosis and treatment primary aldosteronism (PA). PA is most common cause endocrine hypertension. It has been reported 24% selective referred hypertensive patients. Methods We did a search in Pub-Med Google Scholar using terms: PA, hyperaldosteronism, idiopathic adrenal hyperplasia, mineralocorticoid receptor antagonists, adrenalectomy, surgery. also cross-referencing with above terms. had divided our into five sections: Introduction, Diagnosis, Genetics, Treatment, Conclusions. results question answer fashion order make reading more interesting. Results should be searched all high-risk populations. gold standard for plasma aldosterone/plasma renin ratio (ARR). If test positive, then we proceed one four confirmatory tests. localizing technique like vein sampling (AVS) CT scan. lesion unilateral, after proper preoperative preparation, proceed, adrenalectomy. bilateral or patient refuses not fit surgery, treat them usually spironolactone. Conclusions Primary treatable case secondary Only patients unilateral diseases are eligible while non-surgically correctable treated by antagonist (MRA). Thus, distinction between aldosterone hypersecretion crucial.