A systematic review of multisensory cognitive-affective integration in schizophrenia

摘要: Abstract The etymology of schizophrenia implies poor functional integration sensory, cognitive and affective processes. Multisensory (MSI) is a spontaneous perceptual–cognitive process by which relevant information from multiple sensory modalities extracted to generate holistic experience. Deficits in MSI may hinder prompt appropriate behavioural responses complex transient environment. Despite extensive investigation processing patients with schizophrenia, little known about how affected the illness. We systemically searched PubMed electronic database reviewed twenty-nine neuroimaging studies examining schizophrenia. available evidence indicates impaired for non-emotional stimuli especially linguistic information. There also altered emotional stimuli, although findings are inconsistent be modality-specific. Brain alterations superior temporal cortex inferior frontal appear underlie deficits both MSI. limitations experimental paradigms used directions future research discussed.