Enhanced RegIV expression predicts the intrinsic 5-fluorouracil (5-FU) resistance in advanced gastric cancer.
作者： Li-Sha Ying , Jiang-Liu Yu , Xiao-Xiao Lu , Zhi-Qiang Ling
DOI: 10.1007/S10620-012-2381-3
关键词: Advanced gastric cancer 、 Real-time polymerase chain reaction 、 Cancer research 、 Biology 、 Cancer 、 Fluorouracil 、 Hepatology 、 Internal medicine 、 Pancreatitis-Associated Proteins 、 Chemotherapy 、 Molecular biology 、 Drug resistance
摘要: Aim RegIV, a member of the Regenerating (REG) gene family, may be marker for prediction resistance to 5-fluorouracil (5-FU)-based chemotherapy. However, relationship between intrinsic drug gastric cancer (GC) cells 5-FU used alone (single FU) or in multidrug therapeutic regimens (5-FU combinations) and RegIV expression has not been investigated.
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Marja Heiskala, Johanna Arola, Kukka Heiskala, Leif C. Andersson, Expression of Reg IV and Hath1 in neuroendocrine neoplasms. Histology and Histopathology. ,vol. 25, pp. 63- 72 ,(2010) , 10.14670/HH-25.63
Sharon Glaysher, Ian A. Cree, Cell sensitivity assays: the ATP-based tumor chemosensitivity assay. Methods of Molecular Biology. ,vol. 731, pp. 247- 257 ,(2011) , 10.1007/978-1-61779-080-5_21
Hiroyuki Takahashi, Yasuo Takano, Xiao-Han Li, Yang Zheng, Xiang-Hong Yang, Hua-Chuan Zheng, Shinji Masuda, REG IV overexpression in an early stage of colorectal carcinogenesis: an immunohistochemical study. Histology and Histopathology. ,vol. 25, pp. 473- 484 ,(2010) , 10.14670/HH-25.473
Christian M. Kurbacher, Ian A. Cree, Chemosensitivity Testing Using Microplate Adenosine Triphosphate–Based Luminescence Measurements Chemosensitivity. ,vol. 110, pp. 101- 120 ,(2005) , 10.1385/1-59259-869-2:101
Kathryn Vanderlaag, Wei Wang, Laurence Fayadat-Dilman, Janet Wagner, Laura Bald, Jeff Grein, Mary J. Janatpour, Regenerating islet-derived family member, 4 modulates multiple receptor tyrosine kinases and mediators of drug resistance in cancer. International Journal of Cancer. ,vol. 130, pp. 1251- 1263 ,(2012) , 10.1002/IJC.26089
Johan L. Dikken, Cornelis J.H. van de Velde, Daniel G. Coit, Manish A. Shah, Marcel Verheij, Annemieke Cats, Treatment of resectable gastric cancer Therapeutic Advances in Gastroenterology. ,vol. 5, pp. 49- 69 ,(2012) , 10.1177/1756283X11410771
Masashi Fujii, Mitsugu Kochi, Tadatoshi Takayama, Recent advances in chemotherapy for advanced gastric cancer in Japan. Surgery Today. ,vol. 40, pp. 295- 300 ,(2010) , 10.1007/S00595-009-4148-9
Inna V. Fedorenko, Kim H.T. Paraiso, Keiran S.M. Smalley, Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma. Biochemical Pharmacology. ,vol. 82, pp. 201- 209 ,(2011) , 10.1016/J.BCP.2011.05.015
Hidetsugu Yamagishi, Hirokazu Fukui, Akira Sekikawa, Tokuyuki Kono, Shigehiko Fujii, Kazuhito Ichikawa, Shigeki Tomita, Johji Imura, Hideyuki Hiraishi, Tsutomu Chiba, Takahiro Fujimori, Expression profile of REG family proteins REG Iα and REG IV in advanced gastric cancer: Comparison with mucin phenotype and prognostic markers Modern Pathology. ,vol. 22, pp. 906- 913 ,(2009) , 10.1038/MODPATHOL.2009.41
Zhi-Qiang Ling, Pei Li, Ming-Hua Ge, Xuan Zhao, Fu-Jun Hu, Xian-Hua Fang, Zi-Min Dong, Wei-Min Mao, Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer International Journal of Molecular Medicine. ,vol. 27, pp. 625- 635 ,(2011) , 10.3892/IJMM.2011.640