Dually derivatized chitosan nanoparticles and methods of making and using the same
作者： Anthony Cheung , Jun Gao , Eric Hsu
DOI:
关键词: Chitosan 、 In vivo 、 Gene delivery 、 Chemistry 、 Chromatography 、 Arginine 、 Chitosan nanoparticles 、 Gluconic acid
摘要: Provided herein is chitosan dually derivatized with arginine and gluconic acid; methods of making using the same, e.g., for gene delivery in vivo.
lens.org 参考文章(9)
William P. Wiesmann, Snezna Rogelj, Shenda Baker, Ruth Baxter, Nucleic acid delivery using modified chitosans ,(2010)
William P. Wiesmann, Shenda Baker, Shannon Ryan, Chitosan-derivative compounds and methods of controlling microbial populations ,(2007)
Yu Gao, Zhenghong Xu, Shangwei Chen, Wangwen Gu, Lingli Chen, Yaping Li, Arginine-chitosan/DNA self-assemble nanoparticles for gene delivery: In vitro characteristics and transfection efficiency. International Journal of Pharmaceutics. ,vol. 359, pp. 241- 246 ,(2008) , 10.1016/J.IJPHARM.2008.03.037
Shirui Mao, Wei Sun, Thomas Kissel, Chitosan-based formulations for delivery of DNA and siRNA Advanced Drug Delivery Reviews. ,vol. 62, pp. 12- 27 ,(2010) , 10.1016/J.ADDR.2009.08.004
DunWan Zhu, HaiLing Zhang, JinGen Bai, WenGuang Liu, XiGang Leng, CunXian Song, Jian Yang, XiaoWei Li, Xu Jin, LiPing Song, LanXia Liu, XiuLan Li, Yang Zhang, KangDe Yao, Enhancement of transfection efficiency for HeLa cells via incorporating arginine moiety into chitosan Chinese Science Bulletin. ,vol. 52, pp. 3207- 3215 ,(2007) , 10.1007/S11434-007-0455-Y
Jae Hyung Park, Yong Woo Cho, Hesson Chung, Ick Chan Kwon, Seo Young Jeong, Synthesis and characterization of sugar-bearing chitosan derivatives: aqueous solubility and biodegradability. Biomacromolecules. ,vol. 4, pp. 1087- 1091 ,(2003) , 10.1021/BM034094R
Sang Myoung Noh, Sung Sik Bang, Myung-Ok Park, Yu-Kyoung Oh, Myung Suk Kim, Chitosan based polymer conjugate and a method for producing the same ,(2008)
Anthony Cheung, Jun Gao, Eric Hsu, Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo ,(2013)
Kawakami Koei, Takei Takayuki, Nakahara Hideki, HYDROGEL PRODUCED FROM CHITOSAN DERIVATIVE ,(2012)