作者: Bruno Legrand , Gareth John , Bernard Vacher , Florence Castant-Cuisiat
DOI:
关键词: Hydroxy group 、 Medicinal chemistry 、 Alkyl 、 Stereochemistry 、 Hydrogen atom 、 Methyl radical 、 Alkoxy group 、 Chlorine atom 、 Chemistry 、 Fluorine 、 Oxygen atom
摘要: The invention concerns 3-arylthio-propyl-amino-3,4-dihydro-2H-1,5-aryloxathiepin derivatives of general formula (I), wherein: R1 and R2, identical or different, represent a hydrogen atom, fluorine atom chlorine hydroxy group, an alkyl, cyclopropyl, alkoxy, cyclopropoxy radical when they occupy adjacent positions, form with the carbon atoms bearing them carbon-containing cycle oxygen-containing heterocycle five non-aromatic rings; R3 represents alkyl radical, group methoxy radical; R4 methyl R5 R6, different alkylthio, alkylamino groups OR4 carbons which bear six rings containing at least oxygen atom; their pharmaceutically acceptable additions salts.