Co-delivery of rapamycin- and piperine-loaded polymeric nanoparticles for breast cancer treatment

作者: Sameer S Katiyar , Eameema Muntimadugu , Towseef Amin Rafeeqi , Abraham J Domb , Wahid Khan

DOI: 10.3109/10717544.2015.1039667

关键词: PiperinePLGAPharmacologyKineticsMaterials scienceEffluxBioavailabilityMultiple drug resistanceIn vitroChemosensitizer

摘要: … Rapamycin (RPM) is in the clinical trials for breast cancer treatment, but its P-gp substrate … with RPM nanoparticles would be a promising approach in the treatment of breast cancer. …

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