ROLE OF DELAY IN SAMPLE PROCESSING AND OTHER FACTORS IN INTERPRETATION OF CEREBROSPINAL FLUID (CSF) CELL COUNTS IN TRAUMATIC LUMBAR PUNCTURE (LP) FOR SUSPECTED MENINGITIS (M)

作者: Bernhard L Wiedermann , Chris Anna Morgan , Lisa A Kammerman , Pamela R Getson , Wm J Rodriguez

DOI: 10.1203/00006450-198704010-00723

关键词: Experience levelMeningitisCerebrospinal fluidPatient ageTraumatic lumbar punctureInternal medicineSample processingPathologyGastroenterologyMedicinePediatrics, Perinatology, and Child Health

摘要: 276 LP attempts were examined prospectively by physician questionnaire and medical record review. Factors occurring at the time of as well required for CSF receipt laboratory (DEL) compared with clinical variables. Occurrence traumatic increased decreasing experience level person performing (p=0.04) younger patient age (p=0.0002). DEL averaged 28 min, 73% samples ≤ 30 min but 11.5% ≥ 60 DEL. A standard correction formula using RBC count blood WBC counts specimens 10,000 resulted in 11/15 (73%) non-M negative corrected HBC. Percent fresh ranged from 0 to 100 did not correlate (r=0.02). 2 48 M patients had or normal this formula. WBC. Linear regression analysis multiple independent variables (CSF RBC, WBC, DEL) failed produce a meaningful (r=0.47 best fit). Over-correction is likely occur explained Determination percent helpful interpretation suspected M. Mathematical models correct trauma are clinically useful should be used.

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