Ontogeny of platelet function.

摘要: Although the hemostatic potential of adult platelets has been investigated extensively, regulation platelet function during fetal life is less clear. Recent studies have provided increasing evidence for a developmental control ontogeny. Fetal feature distinct differences in reactive properties compared with adults. These very likely reflect modified and homeostatic environment which hyporeactivity contributes to prevent pathological clot formation on one hand but still ensures sufficient hemostasis other hand. In this review, recent findings ontogeny reactivity are summarized, implications clinical practice critically discussed. This includes current platelet-transfusion its risk premature infants neonates.