Neutrophil exosomes enhance the skin autoinflammation in generalized pustular psoriasis via activating keratinocytes

作者: Shuai Shao , Hui Fang , Jingliang Zhang , Man Jiang , Ke Xue

DOI: 10.1096/FJ.201802090RR

关键词: MicrovesiclesGene mutationLymphocyteInflammatory skin diseaseGeneralized pustular psoriasisIn patientImmunologyOlfactomedin-4ChemistryChemokine

摘要: Generalized pustular psoriasis (GPP) is a rare and severe inflammatory skin disease that can be life‐threatening. Gene mutations are found in some cases, but its immune pathogenesis …

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