formation of 9,10-epoxypalmitate and 9,10-dihydroxypalmitate from palmitoleic acid by a soluble system from Bacillusmegaterium

作者: James F. Buchanan , Armand J. Fulco

DOI: 10.1016/0006-291X(78)91138-5

关键词: Palmitoleic acidChromatographyBacillus megateriumCytochromeChemistryBiochemistry

摘要: Abstract A soluble, cytochrome P-450-containing system from Bacillus megaterium which catalyzes the monohydroxylation of long-chain saturated fatty acids has now been found to convert palmitoleic acid 9,10-epoxypalmitate and 9,10-dihydroxypalmitate in addition expected isomeric mixture monohydroxypalmitoleic acids.

参考文章(13)
Masamichi Kusunose, Emi Kusunose, Minor J. Coon, Enzymatic ω-Oxidation of Fatty Acids: I. PRODUCTS OF OCTANOATE, DECANOATE, AND LAURATE OXIDATION Journal of Biological Chemistry. ,vol. 239, pp. 1374- 1380 ,(1964) , 10.1016/S0021-9258(18)91324-4
Masamichi Kusunose, Emi Kusunose, Minor J. Coon, Enzymatic ω-Oxidation of Fatty Acids Journal of Biological Chemistry. ,vol. 239, pp. 2135- 2139 ,(1964) , 10.1016/S0021-9258(20)82211-X
Yoshiro Miura, Armand J. Fulco, (ω–2) Hydroxylation of Fatty Acids by a Soluble System from Bacillus megaterium Journal of Biological Chemistry. ,vol. 249, pp. 1880- 1888 ,(1974) , 10.1016/S0021-9258(19)42868-8
Robert S. Matson, Roberta S. Hare, Armand J. Fulco, Characteristics of a cytochrome P-450-dependent fatty acid ω-2 hydroxylase from Bacillus megaterium Biochimica et Biophysica Acta. ,vol. 487, pp. 487- 494 ,(1977) , 10.1016/0005-2760(77)90218-1
Sheldon W. May, Bernard J. Abbott, Enzymatic epoxidation I. Alkene epoxidation by the ω-hydroxylation system of Pseudomonas oleovorans Biochemical and Biophysical Research Communications. ,vol. 48, pp. 1230- 1234 ,(1972) , 10.1016/0006-291X(72)90842-X
Phillip P. Ho, Armand J. Fulco, Involvement of a single hydroxylase species in the hydroxylation of palmitate at the ω—1, ω—2 and ω—3 positions by a preparation from Bacillus megaterium Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. ,vol. 431, pp. 249- 256 ,(1976) , 10.1016/0005-2760(76)90145-4
Norman C. Chang, Armand J. Fulco, The effects of temperature and fatty acid structure on lipid metabolism in bacillus licheniformis 9259 Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. ,vol. 296, pp. 287- 299 ,(1973) , 10.1016/0005-2760(73)90087-8