Suppressor Cells and Malignancy

作者: David Naor , Jonathan S. Duke-Cohan

DOI: 10.1007/978-1-4613-9558-4_1

关键词: Migration inhibition factorCancer researchNeoplasmTumor rejectionBiologySuppressorReview articleTumor growthMalignancyImmune system

摘要: “Suppressor Cells: Permitters and Promoters of Malignancy?” was the title a review article published by one us in 1979 (1). This paper focused on interrelationships between neoplasm cells regulating immune system. Unfortunately, question mark, which an integral part six years ago, cannot yet be replaced exclamation because mechanisms controlling tumor growth are still unclear. However, intriguing hypothesis that suppressor support growth, their elimination may encourage rejection occupies imagination many immunologists who using variety experimental model systems, both animals humans, order to test above prediction.

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