Evolution of high mutation rates in experimental populations of E. coli

作者: Paul D. Sniegowski , Philip J. Gerrish , Richard E. Lenski

DOI: 10.1038/42701

关键词: PhenotypeFunctional genomicsGenomicsMutation rateGeneticsMutation (genetic algorithm)BiologyAdaptationClonal interferenceEscherichia coliMultidisciplinary

摘要: … such events would be likely to occur in natural populations. When a mutator was introduced … In the evolution experiment we have described here, as in natural populations, mutator …

参考文章(28)
R M Schaaper, R Cornacchio, An Escherichia coli dnaE mutation with suppressor activity toward mutator mutD5. Journal of Bacteriology. ,vol. 174, pp. 1974- 1982 ,(1992) , 10.1128/JB.174.6.1974-1982.1992
Jeffrey H. Miller, A short course in bacterial genetics ,(1992)
P P Pang, A S Lundberg, G C Walker, Identification and characterization of the mutL and mutS gene products of Salmonella typhimurium LT2. Journal of Bacteriology. ,vol. 163, pp. 1007- 1015 ,(1985) , 10.1128/JB.163.3.1007-1015.1985
François Taddei, Miroslav Radman, John Maynard-Smith, Bruno Toupance, Pierre-Henri Gouyon, Bernard Godelle, None, Role of mutator alleles in adaptive evolution Nature. ,vol. 387, pp. 700- 702 ,(1997) , 10.1038/42696
Y Iwasa, A Sasaki, K Ishii, H Matsuda, Evolutionarily stable mutation rate in a periodically changing environment Genetics. ,vol. 121, pp. 163- 174 ,(1989) , 10.1093/GENETICS/121.1.163
P. Nowell, The clonal evolution of tumor cell populations Science. ,vol. 194, pp. 23- 28 ,(1976) , 10.1126/SCIENCE.959840
Richard E. Lenski, Michael R. Rose, Suzanne C. Simpson, Scott C. Tadler, Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations The American Naturalist. ,vol. 138, pp. 1315- 1341 ,(1991) , 10.1086/285289