Postoperative radioiodine ablation in patients with low risk differentiated thyroid carcinoma

摘要: Most patients with newly diagnosed differentiated thyroid carcinoma have tumors low risk of mortality and recurrence. Standard therapy has been total or near thyroidectomy followed by postoperative radioiodine remnant ablation (RRA). Although RRA provides benefits, current clinical guidelines do not recommend it universally, since an increase in disease-free survival a decrease demonstrated so far. Advancements our understanding the biological behavior cancer translated into clinic personalized approach to based on their individual recurrence mortality. Current evidence suggests that is indicated most low-risk patients, especially those papillary carcinomas smaller than 1cm, without extrathyroidal extension, unfavorable histology, lymph node involvement distant metastases. Follow-up these serial measurements serum thyroglobulin neck ultrasound adequate. Careful evaluation all factors relevance will allow more realistic assessment each patient.