Effects of dietary eicosapentaenoate (20:5 n-3) on cardiac beta-adrenergic receptor activity in the marmoset monkey.
作者： Glen S. Patten , Josephine A. Rinaldi , Edward J. McMurchie
DOI: 10.1016/0006-291X(89)92365-6
关键词: Beta-adrenergic receptor activity 、 Marmoset 、 Phospholipid 、 Endocrinology 、 Internal medicine 、 Cholesterol 、 Polyunsaturated fatty acid 、 Eicosapentaenoic acid 、 Unsaturated fatty acid 、 Biology 、 Microsome
摘要: Abstract Eicosapentaenoic acid (EPA; 20:5 n-3; ethyl ester) in combination with atherogenic or non-atherogenic high fat diets was fed to young adult male marmoset monkeys for a period of 30 weeks. EPA markedly reduced the raised plasma cholesterol level evident when feeding an diet but did not influence cardiac membrane cholesterol-to-phospholipid ratio. and its elongation product 22:5 n-3 incorporated into phospholipids at expense linoleic arachidonic acids. Dietary increased β-AR affinity reversed decreased diet.
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