作者: Karsten Schröder , Asmus Meyer-Plath , Dorit Keller , Andreas Ohl
关键词: Polymer chemistry 、 Peek 、 Biomaterial 、 Passivation 、 Polymer 、 Polystyrene 、 Micropatterning 、 Surface modification 、 Polyhydroxyethylmethacrylate 、 Chemical engineering 、 Materials science
摘要: A plasma process sequence has been developed to prepare chemical micropatterns on polymeric biomaterial surfaces. These patterns induce a guided localized cell layover at microscopic dimension. Two subsequent steps are applied. In the first functionalization step microwave ammonia introduces amino groups obtain areas for very good adhesion; second passivation combines pattern generation and creation of repelling areas. This downstream hydrogen removes functional changes linkages polymer chains outermost Similar results have obtained different polymers including polystyrene (PS), polyhydroxyethylmethacrylate (PHEMA), polyetheretherketone (PEEK), polyethyleneterephthalate (PET) polyethylenenaphthalate (PEN). Such rather universal structuring could widen availability biomaterials with specific surface preparations.