Biological Subtypes of Breast Cancer

作者: Sara E. Barnato , William J. Gradishar

DOI: 10.1007/174_2014_1043

关键词: Her2 receptorResponse to treatmentInternal medicineBreast cancerOncologyDiseaseMedicineDNA microarray

摘要: Breast cancer is no longer thought of as a single disease, but rather collection subtypes characterized by molecular signatures. The use gene array analysis has provided insights into the dominant driver pathways that effect individual tumors and translate clinical manifestations response to treatment overall outcome.

参考文章(31)
Gustavo A Viani, Sergio L Afonso, Eduardo J Stefano, Ligia I De Fendi, Francisco V Soares, Adjuvant trastuzumab in the treatment of her-2-positive early breast cancer: a meta-analysis of published randomized trials BMC Cancer. ,vol. 7, pp. 153- 153 ,(2007) , 10.1186/1471-2407-7-153
Neal S. Goldstein, David Decker, Dawn Severson, Scott Schell, Frank Vicini, Jeffrey Margolis, Nayana S. Dekhne, Molecular classification system identifies invasive breast carcinoma patients who are most likely and those who are least likely to achieve a complete pathologic response after neoadjuvant chemotherapy Cancer. ,vol. 110, pp. 1687- 1696 ,(2007) , 10.1002/CNCR.22981
C. Sotiriou, S.-Y. Neo, L. M. McShane, E. L. Korn, P. M. Long, A. Jazaeri, P. Martiat, S. B. Fox, A. L. Harris, E. T. Liu, Breast cancer classification and prognosis based on gene expression profiles from a population-based study Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 10393- 10398 ,(2003) , 10.1073/PNAS.1732912100
A Rody, T Karn, C Solbach, R Gaetje, M Munnes, S Kissler, E Ruckhäberle, GV Minckwitz, S Loibl, U Holtrich, M Kaufmann, None, The erbB2+ cluster of the intrinsic gene set predicts tumor response of breast cancer patients receiving neoadjuvant chemotherapy with docetaxel, doxorubicin and cyclophosphamide within the GEPARTRIO trial. The Breast. ,vol. 16, pp. 235- 240 ,(2007) , 10.1016/J.BREAST.2007.02.006
Seho Park, Ja Seung Koo, Min Suk Kim, Hyung Seok Park, Jun Sang Lee, Jong Seok Lee, Seung Il Kim, Byeong-Woo Park, Characteristics and outcomes according to molecular subtypes of breast cancer as classified by a panel of four biomarkers using immunohistochemistry The Breast. ,vol. 21, pp. 50- 57 ,(2012) , 10.1016/J.BREAST.2011.07.008
Luis A. Fernández-Morales, Miquel A. Seguí, Xavier Andreu, Elsa Dalmau, Amparo Sáez, Carles Pericay, Cristina Santos, Jesús Montesinos, Enrique Gallardo, Angels Arcusa, Eugeni Saigí, Analysis of the Pathologic Response to Primary Chemotherapy in Patients with Locally Advanced Breast Cancer Grouped According to Estrogen Receptor, Progesterone Receptor, and HER2 Status Clinical Breast Cancer. ,vol. 7, pp. 559- 564 ,(2007) , 10.3816/CBC.2007.N.012
Rebecca Dent, Wedad M. Hanna, Maureen Trudeau, Ellen Rawlinson, Ping Sun, Steven A. Narod, Pattern of metastatic spread in triple-negative breast cancer Breast Cancer Research and Treatment. ,vol. 115, pp. 423- 428 ,(2009) , 10.1007/S10549-008-0086-2
Charles M. Perou, Therese Sørlie, Michael B. Eisen, Matt van de Rijn, Stefanie S. Jeffrey, Christian A. Rees, Jonathan R. Pollack, Douglas T. Ross, Hilde Johnsen, Lars A. Akslen, Øystein Fluge, Alexander Pergamenschikov, Cheryl Williams, Shirley X. Zhu, Per E. Lønning, Anne-Lise Børresen-Dale, Patrick O. Brown, David Botstein, Molecular portraits of human breast tumours Nature. ,vol. 406, pp. 747- 752 ,(2000) , 10.1038/35021093
M. Colleoni, G. Viale, D. Zahrieh, L. Bottiglieri, R.D. Gelber, P. Veronesi, A. Balduzzi, R. Torrisi, A. Luini, M. Intra, S. Dellapasqua, A. Cardillo, R. Ghisini, G. Peruzzotti, A. Goldhirsch, Expression of ER, PgR, HER1, HER2, and response: a study of preoperative chemotherapy Annals of Oncology. ,vol. 19, pp. 465- 472 ,(2007) , 10.1093/ANNONC/MDM509
Valentina Guarneri, Kristine Broglio, Shu-Wan Kau, Massimo Cristofanilli, Aman U. Buzdar, Vicente Valero, Thomas Buchholz, Funda Meric, Lavinia Middleton, Gabriel N. Hortobagyi, Ana M. Gonzalez-Angulo, Prognostic Value of Pathologic Complete Response After Primary Chemotherapy in Relation to Hormone Receptor Status and Other Factors Journal of Clinical Oncology. ,vol. 24, pp. 1037- 1044 ,(2006) , 10.1200/JCO.2005.02.6914