Routes to, from and within the subiculum

作者: Claudia Böhm , Yangfan Peng , Jörg R. P. Geiger , Dietmar Schmitz

DOI: 10.1007/S00441-018-2848-4

关键词: Local area networkNeuroscienceUpstream and downstream (transduction)HippocampusPyramidal cellENCODEDefault gatewaySubiculumHippocampus properComputer science

摘要: The subiculum is one of the major output areas hippocampus and has extensive projections to extrahippocampal targets. It likely play a pivotal role in distribution outgoing information from hippocampus. hippocampus, including subiculum, important for formation, consolidation retrieval memory. These functions require network that flexible enough encode incoming also allows reliable distribution, storage integration into previously encoded memories. Finally, relevant be retrieved context-specific manner allow an appropriate behavioral response. as gateway between cortex might serve integrate process proper its other inputs before conveying it more permanent locations. This review summarizes how embedded upstream downstream circuits, describes what known about local topology discusses cellular functional properties subicular cells subtypes. Lastly, these help separate parallel streams distribute multiple target areas.

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