Next-Generation Testing for Cancer Risk: Perceptions, Experiences, and Needs Among Early Adopters in Community Healthcare Settings.
作者： Kathleen R. Blazer , Bita Nehoray , Ilana Solomon , Mariana Niell-Swiller , Julie O. Culver
关键词: Family medicine 、 Perception 、 Healthcare settings 、 Multidisciplinary approach 、 Community of practice 、 Early adopter 、 Test (assessment) 、 Genetic testing 、 Bioinformatics 、 Medicine 、 Tracking (education)
摘要: Background: Advances in next-generation sequencing (NGS) technologies are driving a shift from single-gene to multigene panel testing for clinical genetic cancer risk assessment (GCRA). This study explored perceptions, experiences, and challenges with NGS GCRA among U.S. community-based clinicians. Methods: Surveys delivered at initial 8-month time points, 12-month tracking of cases presented multidisciplinary web-based case conference series, were conducted providers who participated 235-member nationwide community practice. Results: The proportion respondents ordering tests rose 29% survey (27/94) 44% (46/107) within 8 months. Respondents reported significantly less confidence about interpreting counseling compared test results (p < 0.0001 all comparisons). most cited reasons not included concerns utility, communicating results, lack ...
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