Estimation of the prevalence and rate of acute transfusion reactions occurring in Windhoek, Namibia.
作者： Benjamin P.L. Meza , Robert Wilkinson , Matthew J. Kuehnert , David W. Lowrance , Ray W. Shiraishi
DOI: 10.2450/2013.0143-13
关键词: Medical record 、 Clinical trial 、 Blood units 、 Disease control 、 Blood transfusion 、 Confidence interval 、 Medicine 、 Transfusion reaction 、 Pediatrics 、 Multicenter study
摘要: Background Acute transfusion reactions are probably common in sub-Saharan Africa, but reaction surveillance systems have not been widely established. In 2008, the Blood Transfusion Service of Namibia implemented a national acute system, substantial under-reporting was suspected. We estimated actual prevalence and rate occurring Windhoek, Namibia. Methods The percentage events resulting reported calculated. Actual rates per 1,000 transfused units were by reviewing patients' records from six hospitals, which transfuse >99% all blood Windhoek. Patients' for 1,162 between 1(st) January - 31(st) December 2011 randomly selected. Clinical demographic information abstracted Centers Disease Control Prevention National Healthcare Safety Network criteria applied to categorize reactions. Results From 1 31, 2011, there 3,697 (involving 10,338 units) selected hospitals. Eight (0.2%) system. Of selected, medical 785 analysed, 28 detected, only one had also An 3.4% (95% confidence interval [CI]: 2.3-4.4) Windhoek resulted an reaction, with 11.5 CI: 7.6-14.5) units. Conclusion is higher than haemovigilance Improved interventions reduce transfusion-related morbidity mortality required
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