Paracetamol and Phenacetin

作者: Stephen P. Clissold

DOI: 10.2165/00003495-198600324-00005

关键词: AcetaminophenTherapeutic indexAntipyreticMedicinePhenacetinAspirinPharmacologyGastric emptyingAnalgesic nephropathyAnalgesic

摘要: … to paracetamol, it seems possible that phenacetin owes some of its therapeutic activity to its main metabolite, paracetamol, … The mechanism of action of paracetamol is poorly defined, …

参考文章(50)
Gavril W. Pasternak, Michael J. Kuhar, Analgesics : neurochemical, behavioral, and clinical perspectives Raven Press. ,(1984)
W. C. Bowman, M. J. Rand, Textbook of Pharmacology. Textbook of Pharmacology.. ,(1980)
Arena Jm, Rourk Mh, Sibrack Cd, Acetaminophen: report of an unusual poisoning. Pediatrics. ,vol. 61, pp. 68- 72 ,(1978)
James Neuberger, M Davis, Roger Williams, Long-term ingestion of paracetamol and liver disease. Journal of the Royal Society of Medicine. ,vol. 73, pp. 701- 707 ,(1980) , 10.1177/014107688007301004
N C MacDonald, C H Jackson, J W Cornett, Acetaminophen: a practical pharmacologic overview Canadian Medical Association Journal. ,vol. 131, pp. 25- 32 ,(1984)
H. J. Zimmerman, Effects of Aspirin and Acetaminophen on the Liver JAMA Internal Medicine. ,vol. 141, pp. 333- 342 ,(1981) , 10.1001/ARCHINTE.141.3.333
Leo E. Hollister, Perspectives and Summation of Symposium Archives of Internal Medicine. ,vol. 141, pp. 404- 406 ,(1981) , 10.1001/ARCHINTE.1981.00340030136026
Kevin J. Ivey, Gastrointestinal effects of antipyretic analgesics The American Journal of Medicine. ,vol. 75, pp. 53- 64 ,(1983) , 10.1016/0002-9343(83)90233-4
Robert G. Peterson, Age as a Variable in Acetaminophen Overdose Archives of Internal Medicine. ,vol. 141, pp. 390- 393 ,(1981) , 10.1001/ARCHINTE.1981.00340030122022
John A.H. Forrest, J. A. Clements, L. F. Prescott, Clinical Pharmacokinetics of Paracetamol Clinical Pharmacokinectics. ,vol. 7, pp. 93- 107 ,(1982) , 10.2165/00003088-198207020-00001