Tracing the Evolutionary History of Drosophila Regulatory Regions with Models that Identify Transcription Factor Binding Sites

作者: Emmanouil T Dermitzakis , Casey M Bergman , Andrew G Clark

DOI: 10.1093/MOLBEV/MSG077

关键词: Regulatory sequenceGene expressionDrosophila melanogasterBiologyBinding siteGeneChIA-PETTranscription factorGeneticsDNA binding siteEvolutionary biologyEcology, Evolution, Behavior and SystematicsMolecular biology

摘要: … We develop a novel approach to binding site prediction which we use to characterize the process of binding site divergence in regulatory regions. This method uses sets of known …

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