Conditionally immortalized long-term stem cells and methods of making and using such cells

作者: John C. Cambier , Yosef Refaeli , Brian Curtis Turner , Sara Ann Johnson

DOI:

关键词: Cancer researchStem cellCellular differentiationBiologyMyeloid leukemiaImmunologyEmbryonic stem cell

摘要: Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic the cells produced by such methods, therapeutic laboratory or research of using to identify compounds related cell differentiation development treat diseases, cells. A mouse model acute myeloid leukemia (AML) also described.

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